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"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-10-11

Computational Tool Captures How Chromatin Folds at Scale

Studying how chromatin changes requires capturing molecular movements and interactions that are difficult to resolve experimentally. Now, an...

2026-10-09

Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants

Imputing unmeasured fluid intelligence scores in UK Biobank reduces ascertainment bias and increases power for genetic analyses, improving out-of-sample polygenic score performance and identifying rare variant signals that are strongly enriched for intellectual disability-associated genes.

2026-10-05

Single-allele nanoscale mapping of regulatory variants

This study uses high-resolution, allele-specific chromatin architecture to identify causal gene-regulatory mechanisms in inflammatory diseases and uncovers a mechanism by which a neo-CTCF site promotes autoimmunity.

2026-10-02

Single-molecule chromatin tracing reveals a diversity of megabase heterochromatin domains

Single-molecule imaging reveals diverse, megabase-scale heterochromatin domains in C. elegans. Some resemble TADs and depend on condensin I; others are independent of condensin and histone H3K9me, including one domain that encloses the 5S rDNA locus.

2026-10-02

A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity

Koenig et al. present a phosphoproteome atlas of 33 human cell lines covering >200,000 phosphosites, advancing cellular kinase activity scoring and drug sensitivity prediction, providing a resource for cell signaling insights and precision oncology.

2026-09-30

Spatial Transcriptomics and Metabolite Mapping Combined on a Single Tissue Slide

Spatial transcriptomics (ST) shows which genes are active and where within a tissue, while spatial metabolomics (SM) maps the location of...

2026-09-29

Bat1K Consortium Combines Genomes and Fossils to Trace Bat Origins

An international consortium has sequenced and compared 103 bat genomes spanning all 21 recognized bat families, then combined that genomic dataset...

2026-09-25

Microgravity Experiments Reveal Gravity’s Impact on Human Genome Organization

The Human Genome Project, launched in 1990, eventually produced a full sequence of human DNA, but many of the physical rules governing how that...

2026-09-23

Massive Genomic Analysis Maps the Cellular Pathways Driving Psoriasis

A research team led by Hong-Hee Won from Sungkyunkwan University has pinpointed the genetic and cellular mechanisms underlying psoriasis by combining...

2026-09-18