"Познание начинается с удивления" (Аристотель)
Новое в науке на 2024-12-22
Diagnostic prediction is a central application that spans various medical specialties and scenarios, sequential diagnosis prediction is the process of predicting future diagnoses based on patients' historical...
2024-12-20
As a key non-coding RNA molecule, miRNA profoundly affects gene expression regulation and connects to the pathological processes of several kinds of human diseases. However, conventional experimental methods...
2024-12-19
Existing software for comparison of species delimitation models do not provide a (true) metric or distance functions between species delimitation models, nor a way to compare these models in terms of relative...
2024-12-18
Using information measures to infer biological regulatory networks can capture nonlinear relationships between variables. However, it is computationally challenging, and there is a lack of convenient...
2024-12-18
Generating prediction models from high dimensional data often result in large models with many predictors. Causal inference for such models can therefore be difficult or even impossible in practice. The...
2024-12-18
Newborns in the neonatal intensive care unit (NICU) often face severe, life-threatening conditions. For some, extracorporeal membrane oxygenation...
2024-12-17
The authors here show that chromatin interactions during mouse fetal development are spatiotemporally dynamic. Integrating interactomes with other datasets predicts target genes for candidate enhancers and helps interpret noncoding risk variants in the human genome.
2024-12-16
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have introduced iFlpMosaics, an advanced set of genetic tools and mouse...
2024-12-13
Here, the authors describe a noncoding genetic variant in GBA1 specific to people of African ancestry that increases the risk of neurodegenerative diseases by interfering with the splicing of mRNA, resulting in lowered protein levels and activity.
2024-12-12
Xue et al. visualize how the antibiotic chloramphenicol reshapes the translation landscape and induces ribosome collision in bacterial cells, illuminating its context-dependent action across atomic, molecular and cellular scales.
2024-12-12
A recent study has uncovered a brain mechanism that shapes how animals—and potentially humans—respond empathetically to others' emotions. The...
2024-12-12
A recent study published in Molecular Cell has revealed a unique molecular “fingerprint” present in cancer cells, detectable through rapid and...
2024-12-11
Researchers from Kyushu University have provided new insights into DNA movement, spatial organization, and gene activity. Their recent study in...
2024-12-10
