"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-06-03
PGS-TRI, a framework designed for analyzing polygenic scores in case–parent trio studies, allows estimation of the risk of an index condition associated with direct and indirect polygenic effects and related gene–environment interactions.
2026-06-02
Scientists at University Medical Center Utrecht have identified a previously underappreciated mechanism that helps immune cells respond rapidly to...
2026-06-02
DNA methylation is one of the most studied epigenetic modifications, yet its ancestral function in animals and its capacity for transgenerational...
2026-06-02
Scientific publishing is growing faster than any individual researcher can realistically keep up with, and the backlog is creating a real problem....
2026-05-28
Here the authors show that collapse of single replication forks causes recombination, end fusions or degradation but does not restart DNA synthesis. In contrast, collapse of convergent forks completes DNA synthesis through error-prone double-strand break repair.
2026-05-27
For more than 20 years, scientists have understood that cells rely on RNA interference to regulate gene expression. Yet how the molecular complex...
2026-05-26
In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression and promote stress resilience in offspring.
2026-05-22
Ahmed and colleagues show that, by promoting ‘dressing’ of intact tumor target antigens onto dendritic cells, tumor irradiation enhances chimeric antigen receptor T cell persistence and efficacy in lung metastasis models.
2026-05-22
Davidovich et al. investigate allele-specific DNA methylation inheritance patterns in mouse liver and muscle. Most patterns are Mendelian, but ~7% are non-Mendelian, including new imprinted genes and a paramutation at the Capn11 locus.
2026-05-20
Castro-Dopico et al. report the design of reagents to bridge F-actin and Fcγ receptors, endowing a range of antigen-presenting cells with the ability to cross-present antigens from dead tumor cells and boosting antitumor immunity in preclinical models.
2026-05-20
A new artificial intelligence system can automatically write high-performance scientific software, in some cases outperforming programs built by...
2026-05-20
