"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-08-19

Hydrophobic interactions of FG-nucleoporins are required for dilating nuclear membrane pores into selective transport channels after mitosis

Zhang et al. show that FG-nucleoporins self-assemble through hydrophobic interactions to dilate newly assembling nuclear pores after mitosis, enabling nuclear import and nuclear expansion, which in turn remodel the nuclear envelope.

2026-08-18

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Nucleosomes and IDRs suppress promiscuous GCN4 binding on minichromosomes

Wei et al. measure single-molecule kinetics of transcription factor GCN4 on purified yeast minichromosomes to reveal that both nucleosomes and transcription factor intrinsically disordered regions facilitate GCN4 target search on native chromatin by shortening its promiscuous binding.

2026-08-13

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