"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2025-11-27
A large population analysis has identified a mutational hotspot at human transcription start sites. The work, published in Nature Communications,...
2025-11-26
Carty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres.
2025-11-25
A new study in Genomic Psychiatry reports that the deubiquitinase OTULIN shapes tau production by altering gene expression and RNA metabolism,...
2025-11-25
A research team at the University of California San Diego (UCSD) has introduced coralME, a computational tool designed to build genome-scale models...
2025-11-21
Gao et al. present SMMILe, a multiple-instance learning-based tool that leverages whole-slide images for accurate spatial quantification without compromising on classification performance, and show it outperforms state-of-the-art methods.
2025-11-19
Baretić and Missoury et al. identify vertebrate proteins FAM118B and FAM118A as sirtuins similar to bacterial antiphage enzymes and show that FAM118A/B processing of NAD involves head-to-tail filament formation and a partnership between the two paralogs.
2025-11-17
A large Nordic study reports that depression emerging in young adulthood carries a stronger hereditary signal than depression that starts later in...
2025-11-13
Small RNA sequencing (sRNA-seq), long used for profiling microRNAs, may also hold valuable information about messenger RNA expression. A new preprint...
2025-11-12
Majzner and colleagues show that engineering T cells with a membrane-tethered version of the signaling adaptor molecule SLP-76 alongside a chimeric antigen receptor (CAR) enhances CAR T cell activity against low-antigen-density tumors.
2025-10-23
