"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2025-03-14
By using cryo-EM and biochemical assays, Loeff et al. reveal the mechanistic basis for the protective function of the oxidoreductase PYROXD1 that maintains the activity of the tRNA ligase complex under aerobic conditions.
2025-03-11
Mutations in non-coding regulatory regions of DNA may lead to disease through the disruption of transcription factor binding. However, our understanding of binding patterns of transcription factors and the...
2025-03-10
Predicting and studying essential proteins not only helps to understand the fundamental requirements for cell survival and growth regulation mechanisms but also deepens our understanding of disease mechanisms...
2025-03-10
The emergence of next-generation sequencing (NGS) marked a revolution in biological research, enabling comprehensive characterization of the transcriptome and detailed analysis of the epigenome landscape...
2025-03-07
Advanced long-read sequencing technologies, such as those from Oxford Nanopore Technologies and Pacific Biosciences, are finding a wide use in de novo genome sequencing projects. However, long reads typically...
2025-03-07
While alignment has traditionally been the primary approach for establishing homology prior to phylogenetic inference, alignment-free methods offer a simplified alternative, particularly beneficial when...
2025-03-07
A search for new genome-editing tools has led researchers from MIT’s McGovern Institute and the Broad Institute of MIT to identify a distinct class...
2025-03-03
Continuing from our previous article (https://www.seqanswers.com/forum/news/326451-highlights-from-agbt-2025-%E2%80%93-part-i), we’re reviewing the...
2025-02-28
Commemorating 25 years of innovation, the Advances in Genome Biology and Technology (AGBT) conference launched this year’s event at its original...
2025-02-24
A team of researchers led by Jianxin Wang at the School of Computer Science and Engineering, Central South University, conducted an extensive...
2025-02-21
A recent study demonstrates that CRISPR-based gene editing can selectively remove the extra copy of chromosome 21 in human cells. Published as a...
2025-02-18