"Познание начинается с удивления" (Аристотель)
Новое в науке на 2025-12-21
Genome-wide association studies (GWAS) of deep learning-derived measurements of aortic valve function, along with multitrait analyses incorporating disease-based GWAS, identify 166 genetic loci associated with aortic valve function or aortic stenosis.
2025-12-19
Multi-ancestry genome-wide and transcriptome-wide association studies of aortic stenosis identify more than 200 independent risk loci and provide insights into its genetic architecture.
2025-12-19
Diet and drugs are known drivers of the gut microbiome, but the role of host genetics has been more challenging to determine. A study in Nature...
2025-12-19
Chemists at the University of Massachusetts Amherst have developed a fluorescent imaging approach that allows multiple messenger RNA molecules to be...
2025-12-19
Npm1 promotes tumor formation via attenuating the integrated stress response and p53 activation in mouse WNT-driven intestinal and liver tumorigenesis.
2025-12-18
How cells maintain a consistent size has remained a basic unanswered question in biology, despite clear links between abnormal cell size and disease....
2025-12-18
A large-scale genetic analysis suggests that many psychiatric diagnoses rest on a smaller set of shared biological factors than clinical categories...
2025-12-12
Alcohol use remains common in the United States, yet its role in cancer risk is often understated in public health guidance. A new systematic review...
2025-12-12
Zeng et al. applied single-particle cryo-electron microscopy to native samples isolated from the human parasite Toxoplasma gondii, determining multiple structures of key components of the conoid, a cone-shaped organelle essential for host cell invasion.
2025-12-09
Riechmann et al. uncover structural features governing ubiquitin transfer from ubiquitin-activating E1 enzymes UBA1 and UBA6 to specific E2 ubiquitin-conjugating enzymes, revealing a hierarchy of E2 activity with cognate E1s.
2025-12-05
