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"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-09-12

Contribution of copy number variants to schizophrenia in East Asian populations

Genomic analyses in populations of East Asian ancestry identify rare copy number variants associated with schizophrenia. Meta-analyses with populations of European ancestry identify additional risk loci enriched in genes less tolerant to loss-of-function variants.

2026-09-11

Cancer treatment alters mutant selection in normal esophagus

Cancer treatment alters the selection of preexisting somatic mutations in the normal esophagus, including druggable mutants that confer treatment resilience to normal cells.

2026-09-11

Commensal Nakaseomyces glabratus migrates into prostate tumors to accelerate cancer progression

Lai et al. show that Nakaseomyces glabratus is enriched in fecal and tumor samples of patients with castration-resistant prostate cancer and that administration of the fungus accelerates cancer progression in prostate cancer-bearing castrated mice.

2026-09-09

Study Confirms DNA Zipper Model of Strand Pairing

Like charges normally repel one another, yet DNA molecules must pair up inside living cells to carry out essential biological processes, including...

2026-09-09

Berkeley Team Builds Genomic Language Model to Pinpoint Key Genetic Variants

More than two decades after scientists first sequenced the human genome’s 3 billion DNA letters, most of that code’s meaning remains unclear. Only 1...

2026-09-09

Study Links Five Chronic Fatigue Disorders to Shared Biological Architecture

Researchers at the University of East Anglia have identified shared biological mechanisms that may help explain chronic exhaustion in conditions...

2026-09-03

Newly Discovered Chimeric Proteins Found to Play Roles Throughout the Body

Scientists have long understood that each of the roughly 20,000 genes in the human body carries the instructions for a single kind of protein....

2026-09-02

Molecular architecture and spatial organization of proteasomes in the human sperm nucleus

Proteasomes are essential for male fertility. Kolata, dos Santos, Dendooven and colleagues show large nuclear proteasomal assemblies segregated from DNA in human sperm, forming after meiosis and with a unique α4s isoform. A native substrate is bound at the 20S catalytic site.

2026-09-01

l-Glutamine in combination with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ductal adenocarcinoma: an open-label, single-arm, phase 1 GlutaPanc trial

In this open-label, single-arm, phase 1 GlutaPanc trial, Gong and colleagues report the safety and feasibility of l-glutamine in participants with advanced pancreatic ductal adenocarcinoma and determine the recommended phase 2 dose of l-glutamine in combination with gemcitabine and nab-paclitaxel.

2026-08-31

Galanin impairs tumor immunity in glioblastoma by promoting infiltration and ferroptosis resistance of myeloid-derived suppressor cells

Chen and colleagues report that the neuropeptide galanin impairs antitumor immunity in glioblastoma by interacting with its receptor GALR3 on monocytic myeloid-derived suppressor cells, promoting their infiltration and ferroptosis resistance.

2026-08-25

Giant Sunflower Genomes Advance the Case for Climate-Resilient Perennial Crops

Researchers at the Land Institute and the HudsonAlpha Institute for Biotechnology have produced the first chromosome-scale, haplotype-phased genome...

2026-08-24