"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-10-16
A Mayo Clinic-led study has shown how to detect a broad range of DNA mutations in noncancerous human tissues and across the genome. The analysis,...
2026-10-15
Kjer-Hansen et al. show that alternative splicing reshapes how proteins interact and where they localize in cells, with tiny microexons making a disproportionate contribution to protein organization and cellular function.
2026-10-14
Living human cells appear to hold the local movement of their DNA at a remarkably steady level through most of the cell cycle, only dialing it up...
2026-10-14
Klose et al. provide structural insights into a supercomplex between the EMC and Spf1 that brings together cellular machines for membrane protein insertion and extraction into a single entity, providing a framework for integrated membrane protein quality control.
2026-10-13
Most GWAS loci fall in regions that control gene expression rather than in the genes themselves, and linking those variants to eQTL and sQTL signals...
2026-10-13
Studying how chromatin changes requires capturing molecular movements and interactions that are difficult to resolve experimentally. Now, an...
2026-10-09
Imputing unmeasured fluid intelligence scores in UK Biobank reduces ascertainment bias and increases power for genetic analyses, improving out-of-sample polygenic score performance and identifying rare variant signals that are strongly enriched for intellectual disability-associated genes.
2026-10-05
Single-molecule imaging reveals diverse, megabase-scale heterochromatin domains in C. elegans. Some resemble TADs and depend on condensin I; others are independent of condensin and histone H3K9me, including one domain that encloses the 5S rDNA locus.
2026-10-02
Spatial transcriptomics (ST) shows which genes are active and where within a tissue, while spatial metabolomics (SM) maps the location of...
2026-09-29
