"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2025-12-14
A large-scale genetic analysis suggests that many psychiatric diagnoses rest on a smaller set of shared biological factors than clinical categories...
2025-12-12
Alcohol use remains common in the United States, yet its role in cancer risk is often understated in public health guidance. A new systematic review...
2025-12-12
Linking genetic variants to disease remains a central challenge in human genetics, especially for traits influenced by many genes. A study published...
2025-12-12
DNA methylation and copy number variant analyses across a large number of genetic mouse models of pediatric brain tumors reveal subtype-specific molecular alterations shared with the corresponding human diseases.
2025-12-11
Zeng et al. applied single-particle cryo-electron microscopy to native samples isolated from the human parasite Toxoplasma gondii, determining multiple structures of key components of the conoid, a cone-shaped organelle essential for host cell invasion.
2025-12-09
Riechmann et al. uncover structural features governing ubiquitin transfer from ubiquitin-activating E1 enzymes UBA1 and UBA6 to specific E2 ubiquitin-conjugating enzymes, revealing a hierarchy of E2 activity with cognate E1s.
2025-12-05
Mitochondrial translational activators (TAs) facilitate transcript-specific translation. Using selective ribosome profiling and cryo-electron microscopy, the authors show that TAs bind to the 5′ untranslated region of their target transcript to position mitoribosomes for initiation.
2025-12-03
A new study in Nature Communications presents a detailed look at how a self-splicing ribozyme builds its functional structure. The work, led by Marco...
2025-12-01
A large population analysis has identified a mutational hotspot at human transcription start sites. The work, published in Nature Communications,...
2025-11-26
