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"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-05-11

Audit Finds Fake References in Medical Papers

A new Columbia University School of Nursing audit has found nearly 3,000 peer-reviewed medical papers with fake citations that do not exist in...

2026-05-08

Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed

Schöndorf and Petrychenko et al. show that mitochondrial translation speed is coupled to OXA1L-mediated inner membrane insertion, with cotranslational nascent chain folding and insertion driving structural changes and translational pausing.

2026-05-07

Study Reveals HELQ Promotes Replication Fork Remodeling

During cell division, DNA replication faces constant threats from interstrand crosslinks (ICLs) that chemically fuse DNA strands, halting the...

2026-05-07

Structural basis for recognition of diverse localizing mRNAs by Egl–BicD

Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional sequence information and number of structured RNA elements.

2026-05-05

New Method Enables Non-Destructive Tracking of Gene Expression

A research team led by Gil Westmeyer at the Technical University of Munich (TUM) has developed a method that allows scientists to analyze gene...

2026-05-05

Tumor-localized CD40 agonism with MP0317, a FAP x CD40 DARPin, reprograms the tumor microenvironment in patients with advanced solid tumors: an open-label, nonrandomized, dose-escalation phase 1 study

In this paper, Steeghs and colleagues report the safety, activity, pharmacokinetic and pharmacodynamic results of a phase 1 dose-escalation trial with MP0317 (FAP x CD40 DARPin) monotherapy in patients with advanced solid tumors.

2026-05-01

Nucleosome Structure Shapes DNA Accessibility in Cells, Study

Every human cell compacts more than six feet of DNA into a microscopic space by wrapping it around protein complexes known as nucleosomes. This...

2026-04-29

Single-Cell Sequencing Tracks Immune Cells Inside Lung Tumors

Researchers at VIB and VUB have developed a sequencing-driven approach to study how immune cells behave within lung tumors. By combining a...

2026-04-27