"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2024-11-07
The prediction of protein–protein interaction sites plays a crucial role in biochemical processes. Investigating the interaction between viruses and receptor proteins through biological techniques aids in...
2024-11-04
The construction of a pangenome graph is a fundamental task in pangenomics. A natural theoretical question is how to formalize the computational problem of building an optimal pangenome graph, making explicit...
2024-11-04
G-protein coupled receptors (GPCRs), the largest family of membrane proteins in human body, involve a great variety of biological processes and thus have become highly valuable drug targets. By binding with...
2024-11-04
The maximal sensitivity for local pairwise alignment makes the Smith-Waterman algorithm a popular choice for protein sequence database search. However, its quadratic time complexity makes it...
2024-11-02
The study focuses on enhancing the effectiveness of precision agriculture through the application of deep learning technologies. Precision agriculture, which aims to optimize farming practices by monitoring...
2024-11-01
University of Michigan researchers have refined a unique approach for visualizing gene expression at unprecedented resolution, marking a major...
2024-11-01
Snyder and colleagues show global loss of promoter–enhancer connectivity during early colorectal carcinogenesis and the dependency of gene dysregulation during this process on the baseline of promoter–enhancer interaction in normal colonic epithelium.
2024-10-30
Snyder and colleagues present a comprehensive multiomic atlas of normal mucosal, benign polyps and dysplastic polyps from six persons with familial adenomatous polyposis, comprising transcriptomic, proteomic, metabolomic and lipidomic datasets.
2024-10-30
Ding and colleagues use bulk, single-cell and single-nucleus multi-omics together with spatial transcriptomics and multiplex imaging of clinical tumor samples to characterize gene expression and chromatin accessibility of breast cancer lineages.
2024-10-30
Scientists have long relied on statistical models to predict disease risks and uncover genetic associations, yet many of these tools function as...
2024-10-30
A recent study published in Cellular & Molecular Immunology suggests that a small subset of blood stem cells plays a key role in determining the...
2024-10-24
A collaboration between scientists at The Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University has led to the...
2024-10-23
Urban environments, defined by their dense infrastructure and human activity, may be influencing the evolution of microorganisms that inhabit them. A...
2024-10-17