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"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-07-01

Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity

Segura-Bayona et al. uncover genetically separable ATRX functions that independently safeguard telomeres and genome replication, revealing how CST and 9-1-1 pathways suppress accumulation of toxic single-stranded DNA and preserve chromosome integrity.

2026-06-30

New AI Model Captures Long-Range Genomic Signals to Improve RNA Splice Site Prediction

A deep learning model developed at the University of Tokyo can analyze DNA sequences spanning up to 100,000 base pairs to predict RNA splice sites...

2026-06-30

No evidence of immunosurveillance in mutation-hotspot-driven clonal hematopoiesis

Analysis of the UK Biobank cohort demonstrates that there is no significant MHC-I- or MHC-II-driven negative selection against expansion of mutant clones in clonal hematopoiesis.

2026-06-29

Large-Scale Protein Screen Uncovers Hidden Regulators of Alternative Polyadenylation

A team at the University of California San Diego has developed a large-scale screening approach that identifies proteins controlling alternative...

2026-06-26

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation

The authors use single-cell multi-omics to interrogate longitudinal samples of isocitrate dehydrogenase mutant gliomas. Their analyses couple progression and hypomethylation with changes in differentiation topologies and increased emergence of stem-like states in aggressive disease.

2026-06-22

Whole-Genome Sequencing Traces Faroe Islands Ancestry to a North Atlantic Founder Population

Whole-genome sequencing of 40 individuals from the Faroe Islands has shed new light on how this remote North Atlantic population descended from an...

2026-06-17

Sequencing the Two-Toed Sloth Genome Reveals Jumping Genes Tied to Its Extreme Metabolism

Sloths are the slowest mammals on Earth, and their dense jungle habitat has made them notoriously difficult to study. Now, for the first time,...

2026-06-09

A New Method Makes Hantavirus Genome Analysis Faster and More Accessible

Hantavirus infections are rare—roughly 30 people are infected in the United States each year—but they are deadly, killing 30 to 40 percent of those...

2026-06-05