Site logo

"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-07-25

Nanoparticle-enriched mass spectrometry proteomics in British South Asians identifies links between genetic variants, plasma protein levels and disease risk

This study reports genetic effects on mass spectrophotometry-based plasma proteomics in a cohort of ~1,400 British South Asians, accessing parts of the proteome missed by other proteomics platforms. The resulting protein quantitative trait loci are integrated with genome-wide association study data to find potential mechanisms of disease.

2026-07-24

Study Captures the First Moments of DNA Replication

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have identified one of the earliest steps in DNA replication: the...

2026-07-24

Chemotherapy Leaves Detectable DNA Signatures in Childhood Tumors

A study (https://www.nature.com/articles/s41586-026-10803-1) led by The Hospital for Sick Children (SickKids), published in Nature, found that nearly...

2026-07-23

A pangenome of tetraploid wheat reveals the genetic architecture underlying domestication and genomic diversity for breeding

A pangenome of tetraploid wheat constructed from 12 de novo genome assemblies spanning 10 subspecies, integrating with whole-genome sequencing data, highlights genetic variation associated with agricultural traits.

2026-07-22

Structural and functional basis of antinociceptive action of χ-conotoxin AoIA at the noradrenaline transporter

Belleza, Zhang and colleagues showed that the χ-conotoxin χ-AoIA, a venom-derived peptide, reduces pain in mice by blocking the norepinephrine transporter more effectively than other similar peptides.

2026-07-21

Single-Cell Atlases Skew Toward European Ancestry, Analysis Finds

A study led by researchers at the Icahn School of Medicine at Mount Sinai finds that single-cell atlases do not fairly represent the world’...

2026-07-20

Conformational plasticity of human acid-sensing ion channel 1a

Using cryo-electron microscopy, Cahill, Hartfield et al. identified six structural states of human acid-sensing ion channel 1a, revealing how acidic conditions and peptide toxins regulate channel activation and desensitization through conformational flexibility.

2026-07-16

UC San Diego Bioengineers Map Gene Function in Human Stem Cells

Bioengineers at the University of California San Diego have developed a genome-scale reference map showing how individual genes control the functions...

2026-07-13

New Analysis Splits Leukemia Into 16 Epigenomic Subgroups

Acute myeloid leukemia (AML) is one of the most aggressive of all blood cancers, and how it is classified helps determine how each patient is...

2026-07-09