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"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-05-22

Non-Mendelian inheritance of DNA methylation patterns in mice

Davidovich et al. investigate allele-specific DNA methylation inheritance patterns in mouse liver and muscle. Most patterns are Mendelian, but ~7% are non-Mendelian, including new imprinted genes and a paramutation at the Capn11 locus.

2026-05-20

Coupling dead cell recognition to Fcγ receptors augments anticancer immunity

Castro-Dopico et al. report the design of reagents to bridge F-actin and Fcγ receptors, endowing a range of antigen-presenting cells with the ability to cross-present antigens from dead tumor cells and boosting antitumor immunity in preclinical models.

2026-05-20

AI System Writes Scientific Software That Outperforms Human-Designed Code

A new artificial intelligence system can automatically write high-performance scientific software, in some cases outperforming programs built by...

2026-05-20

eDNA Sequencing Reveals Genetic Diversity in Wild Dolphin Schools

DNA permeates the world's oceans, both packaged inside cells shed as skin, scales, mucous, feces, and blood, and floating freely in the water....

2026-05-19

DNA-Guided CRISPR System Offers Cheaper and More Precise RNA Targeting

For years, scientists have steered CRISPR enzymes toward their targets using RNA guides. Engineers at the University of Florida have now flipped that...

2026-05-18

Combined ctDNA and serum PSA for dynamic monitoring of metastatic prostate cancer starting first-line treatment: a prospective national cohort study

Jayaram et al. assessed the performance of the combination of circulating tumor DNA and serum prostate-specific antigen for dynamic monitoring of metastatic prostate cancer at first-line treatment in this prospective observational clinical trial.

2026-05-15

Large Genomic Survey Flags Worsening Carbapenem Resistance Across Europe

The largest European genomic survey of carbapenem- and/or colistin-resistant Enterobacterales (CCRE) to date paints a worrying picture of carbapenem...

2026-05-13

Genome Duplications Helped Flowering Plants Survive Ancient Mass Extinctions

When an asteroid struck Earth 66 million years ago, it eliminated all non-avian dinosaurs and roughly one-third of life on the planet. Many flowering...

2026-05-11

Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed

Schöndorf and Petrychenko et al. show that mitochondrial translation speed is coupled to OXA1L-mediated inner membrane insertion, with cotranslational nascent chain folding and insertion driving structural changes and translational pausing.

2026-05-07

Structural basis for recognition of diverse localizing mRNAs by Egl–BicD

Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional sequence information and number of structured RNA elements.

2026-05-05