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"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-04-29

TMPRSS2-mediated coronavirus spike activation and inhibition

Here, the authors elucidate TMPRSS2 protease recognition of the SARS-CoV-2 spike S2′ cleavage site, revealing the molecular basis of activation of membrane fusion, and show that antibodies recognizing the S2′ site or TMPRSS2 block viral entry by interfering with TMPRSS2 access.

2026-04-28

Single-Cell Sequencing Tracks Immune Cells Inside Lung Tumors

Researchers at VIB and VUB have developed a sequencing-driven approach to study how immune cells behave within lung tumors. By combining a...

2026-04-27

Telomere-to-telomere genome assemblies and population resequencing of diploid and allotetraploid peanut varieties

Telomere-to-telomere genome assemblies for two diploid and four tetraploid peanut varieties provide insights into peanut genome organization, evolutionary dynamics and phenotypic differentiation.

2026-04-24

International Team Sequences the Genomes of Indigenous Peoples Across the Americas

An international research team has sequenced the largest genomic dataset yet assembled for Indigenous peoples of the Americas, generating 199 genomes...

2026-04-22

TMEM87A suppresses ferroptosis and increases cancer immunotherapy resistance by maintaining the Golgi apparatus pH homeostasis

Li et al. show that TMEM87a maintains the Golgi pH homeostasis in response to ferroptosis-induced Golgi lipid peroxidation. TMEM87a ablation sensitizes multiple cancer types to ferroptosis, increasing antitumor immunity and response to immunotherapy.

2026-04-21

Sequencing Reveals Hidden Mutations in Autoimmune Disease

New research suggests that autoimmune diseases may be driven by DNA changes in immune cells that remove natural restraints on the immune system. The...

2026-04-15

Engineers Develop Compact CRISPR Nuclease for In-Body Editing

Clinical use of CRISPR-based gene editing has mostly involved modifying cells outside the body before reintroducing them. A key challenge has been...

2026-04-13

CIPHER-seq Reveals Immune Cell Activity

A new single-cell method called CIPHER-seq is giving scientists an unprecedented view of immune cell behavior, connecting genetic signals to...

2026-04-08