"Познание начинается с удивления" (Аристотель)
Новое в науке на 2025-04-03
A team in Japan has developed a graphical software tool that helps biologists estimate 3D gene expression patterns across tissue samples without the...
2025-04-02
Chromatin loops are critical for the three-dimensional organization of the genome and gene regulation. Accurate identification of chromatin loops is essential for understanding the regulatory mechanisms in...
2025-04-01
Machine learning is frequently used to make decisions based on big data. Among these techniques, random forest is particularly prominent. Although random forest is known to have many advantages, one aspect...
2025-03-31
The advent of high-throughput sequencing technologies, such as DNA microarray and DNA sequencing, has enabled effective analysis of cancer subtypes and targeted treatment. Furthermore, numerous studies have...
2025-03-28
Understanding the metabolic activities of the gut microbiome is vital for deciphering its impact on human health. While direct measurement of these metabolites through metabolomics is effective, it is often...
2025-03-27
As single-cell genomics experiments increase in complexity and scale, the need to integrate multiple datasets has grown. Such integration enhances cellular feature identification by leveraging larger data...
2025-03-27
A new AI tool from University of Florida researchers generates detailed 3D mouse brain maps, offering a zoomable view of energy-producing molecules....
2025-03-20
Gene transfer is an important mechanism used by bacteria to exchange genetic material. This can allow these microorganisms to adapt to different...
2025-03-19
Small nucleolar RNAs (snoRNAs) are a group of non-coding RNAs that have shown important roles in cellular functions and disease associations....
2025-03-18
The BRCC36 isopeptidase complex (BRISC) is a deubiquitylase that stabilizes interferon receptors, driving inflammation. We discovered ‘BRISC molecular glue’ inhibitors (BLUEs) that selectively inactivate BRISC, promoting interferon receptor ubiquitylation and degradation to dampen immune responses.
2025-03-17
A search for new genome-editing tools has led researchers from MIT’s McGovern Institute and the Broad Institute of MIT to identify a distinct class...
2025-03-03
