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"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-04-23

International Team Sequences the Genomes of Indigenous Peoples Across the Americas

An international research team has sequenced the largest genomic dataset yet assembled for Indigenous peoples of the Americas, generating 199 genomes...

2026-04-22

TMEM87A suppresses ferroptosis and increases cancer immunotherapy resistance by maintaining the Golgi apparatus pH homeostasis

Li et al. show that TMEM87a maintains the Golgi pH homeostasis in response to ferroptosis-induced Golgi lipid peroxidation. TMEM87a ablation sensitizes multiple cancer types to ferroptosis, increasing antitumor immunity and response to immunotherapy.

2026-04-21

Sequencing Reveals Hidden Mutations in Autoimmune Disease

New research suggests that autoimmune diseases may be driven by DNA changes in immune cells that remove natural restraints on the immune system. The...

2026-04-15

Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency

Guan, Ocampo and colleagues report the discovery and mechanistic dissection of Al3Cas12f, a metagenome-derived miniature nuclease that retains notable genome-editing capacity. They engineer an RKK variant, which boosts editing and helps overcome the potency threshold that has limited compact editors.

2026-04-13

Engineers Develop Compact CRISPR Nuclease for In-Body Editing

Clinical use of CRISPR-based gene editing has mostly involved modifying cells outside the body before reintroducing them. A key challenge has been...

2026-04-13

CIPHER-seq Reveals Immune Cell Activity

A new single-cell method called CIPHER-seq is giving scientists an unprecedented view of immune cell behavior, connecting genetic signals to...

2026-04-08

WGS Confirms P. ransonneti Lacks Luciferase Gene and Steals Bioluminescence from Prey

Whole-genome sequencing has provided definitive proof that the fish Parapriacanthus ransonneti lacks the luciferase gene essential for...

2026-04-06