"Познание начинается с удивления" (Аристотель)
Новое в науке на 2026-08-26
Researchers used AI to design synthetic transcriptional enhancers that are active in specific tissues in mammals and validated their function in mice. This type of approach could enable advanced gene expression control in synthetic biology and gene therapy.
2026-08-25
Chen and colleagues report that the neuropeptide galanin impairs antitumor immunity in glioblastoma by interacting with its receptor GALR3 on monocytic myeloid-derived suppressor cells, promoting their infiltration and ferroptosis resistance.
2026-08-25
Researchers at the Land Institute and the HudsonAlpha Institute for Biotechnology have produced the first chromosome-scale, haplotype-phased genome...
2026-08-24
A study (https://www.science.org/doi/10.1126/sciadv.adz5561) published in Science Advances by researchers at the University of Vienna maps how genome...
2026-08-20
Zhang et al. show that FG-nucleoporins self-assemble through hydrophobic interactions to dilate newly assembling nuclear pores after mitosis, enabling nuclear import and nuclear expansion, which in turn remodel the nuclear envelope.
2026-08-18
Aging is a major risk factor for many diseases, but reliable methods for measuring how quickly cells age have been lacking. Now, researchers at...
2026-08-18
Wei et al. measure single-molecule kinetics of transcription factor GCN4 on purified yeast minichromosomes to reveal that both nucleosomes and transcription factor intrinsically disordered regions facilitate GCN4 target search on native chromatin by shortening its promiscuous binding.
2026-08-13
An unhealed wound leaves a scar. In the genome, an unrepaired DNA lesion leaves a mutation — a permanent edit to the genetic code. Mutations can...
2026-08-13
Scientists at St. Jude Children’s Research Hospital have built a single-cell atlas of V1 interneurons, a key class of spinal neurons involved in...
2026-08-11
