"Жизнь коротка, наука -- бесконечна" (Гиппократ)
Новое в науке на 2026-02-04
A multitrait fine-mapping method, mvSuSiE, improves power and resolution over single-trait methods for identifying putative causal variants from genetic association data.
2026-02-03
Antigen presentation in skull bone marrow by hematopoietic stem and progenitor cells induces myelopoiesis and generates CD4+ regulatory T cells in a mouse model of ependymoma, promoting immune tolerance. Treatment with anti-GM-CSF antibody has antitumor effects that are augmented by immunotherapy.
2026-02-03
Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism underlying genetic risk for these disorders.
2026-02-03
Saturation genome editing of a cancer mutation hotspot in CTNNB1, the gene encoding β-catenin, reveals a gradient of effects of missense mutations on Wnt signaling.
2026-02-02
Ribas and colleagues report the results of a phase 2 clinical trial of neoadjuvant PD-1 blockade in patients with surgically resectable desmoplastic melanoma.
2026-01-29
A single-cell epigenomic atlas of human immune cells highlights cell-type-specific features associated with genetic or environmental exposures.
2026-01-27
